In Canada today, approximately 7% of infants are born preterm. Approximately half of these infants are exposed to multiple courses of antenatal corticosteroids (ACS). A randomized controlled trial, Multiple Courses of Antenatal Corticosteroids for Preterm Birth Study (MACS), was completed to determine the effectiveness of this important antenatal treatment.
The Multiple Courses of Antenatal Corticosteroids for Preterm Birth Study: A 5-year Follow-up (MACS-5), is an international multi-centre trial assessing 1200 children from the original MACS study at 5 years of age. The MACS-5 study aims to determine the long-term effects of antenatal corticosteroids with emphasis on cognitive, behavioural and motor development.
Click here to visit the MACS-5 blog.